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DePaolo Lab & BuzzFeed answer some important questions.

Projects.

Inflammatory Bowel Disease (IBD) & Associated Cancers.

Molecular Nutrition.

Art & Science.

Publications.

The Dynamic Microbial Landscape of the Intestine and its Impact on Probiotic Therapy

The Dynamic Microbial Landscape of the Intestine and its Impact on Probiotic Therapy.

Denise Chac and R. William DePaolo

– Journal of Probiotics and Health

Infection, genetics & inflammation set the stage for chronic inflammation

Genetic and Metabolic Signals during Acute Enteric Bacterial Infection Alter the Microbiota and Drive Progression to Chronic Inflammatory Disease.

Karishma Kamdar, Samira Khakpour, Jingyu Chen, Vanessa Leone, Jennifer Brulc, Thomas Mangatu, Dionysios A. Antonopoulos, Eugene B. Chang, Stacy A. Kahn, Barbara S. Kirschner, Glenn Young, R. William DePaolo

– Cell Host & Microbe

Intestinal inflammation can be worsened by vitamin A (Celiac disease)

Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens.

DePaolo RW, Abadie V, Tang F, Fehlner-Peach H, Hall JA, Wang W, Marietta EV, Kasarda DD, Waldmann TA, Murray JA, Semrad C, Kupfer SS, Belkaid Y, Guandalini S, Jabri B

– Nature